Prescription drug monitoring program mandates: Comprehensive mandates for prescription drug monitoring programs reduce opioid prescriptions and hospital use

States that require prescribers to register with and use prescription drug monitoring programs in most clinical circumstances saw notably fewer opioid prescriptions and reduced opioid-related hospital use by Medicaid patients compared to states with weak

A novel technology for genome-editing a broad range of mutations in live organisms: Scientists develop a new gene-editing tool that could help treat many disorders caused by gene mutations

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such

3q29 deletion survey: Distinct social profile, high ASD risk: Chromosomal deletion connected to both schizophrenia + autism

A survey of 93 people with 3q29 deletion syndrome reveals a distinct pattern of social disability and anxiety, even without a diagnosis of autism spectrum disorder. The results were published online in Molecular Autism on

Decentralizing science may lead to more reliable results in biomedical research: Analysis of data on tens of thousands of drug-gene interactions

Research results on drug-gene interactions are much less likely to be replicated if they are performed by hierarchical communities or close-knit groups of frequent collaborators who use similar methods, instead of independent groups of scientists

Applying the Goldilocks principle to DNA structure: Scientists consider the form that may be ‘just right’ for scripting gene expression

The Goldilocks of fairy-tale fame knew something about porridge. It needed to be just right — neither too hot nor too cold. Same with furniture — neither too hard nor too soft. In a different