(HealthDay)—Routine urine samples can be used to test for medication adherence in patients with type 2 diabetes, according to a study published in the June issue of Diabetes Care.
Prashanth Patel, M.B.B.S., from the University Hospitals of Leicester NHS Trust in the United Kingdom, and colleagues used liquid chromatography-tandem mass spectrometry analysis to measure nonadherence to cardiovascular medications in urine samples from 228 patients with type 2 diabetes seen in primary care for an annual diabetes review.
The researchers found that 28.1 percent of patients were nonadherent to antidiabetic, antihypertensive, and/or lipid-lowering medications. Statin nonadherence was highest (23.7 percent), while nonadherence to oral hypoglycemic agents was lowest (9.3 percent). In nonadherent patients, hemoglobin A1c, albumin-to-creatinine ratio, and lipid profiles were significantly higher compared to those seen in patients adherent to treatment.
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