Applying the Goldilocks principle to DNA structure: Scientists consider the form that may be ‘just right’ for scripting gene expression

The Goldilocks of fairy-tale fame knew something about porridge. It needed to be just right — neither too hot nor too cold. Same with furniture — neither too hard nor too soft. In a different

Engineered DNA vaccine protects against emerging Mayaro virus infection: New vaccine induces robust and specific immune responses and provides complete protection from disease in preclinical studies

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.