Applying the Goldilocks principle to DNA structure: Scientists consider the form that may be ‘just right’ for scripting gene expression

The Goldilocks of fairy-tale fame knew something about porridge. It needed to be just right — neither too hot nor too cold. Same with furniture — neither too hard nor too soft. In a different

New computational tool harnesses big data, deep learning to reveal dark matter of the transcriptome: Researchers create a new tool for scientists to advance disease diagnosis and treatment

A research team at Children’s Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when copied from DNA. Because

Engineered DNA vaccine protects against emerging Mayaro virus infection: New vaccine induces robust and specific immune responses and provides complete protection from disease in preclinical studies

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.